A pioneering Indian modernist, Mukherjee blended imagery and iconography from Indian life with a signature visual style influenced by Indian, East Asian, and Western art practices and traditions. Mukherjee studied with the celebrated artist Nandalal Bose as one of the first students at the renowned Kala Bhavana, the fine-arts institute founded by the poet Rabindranath Tagore at Visva-Bharati University in Santiniketan, West Bengal. The curriculum of Kala Bhavana was structured similarly to that of the German Bauhaus (Tagore travelled to Europe often, and he visited the Weimar Bauhaus in 1921), with students encouraged to explore form and style in an open manner with various mentors. Rather than depicting mythological or nationalistic imagery, common themes and subjects among Indian artists at this time, Mukherjee examined nature and his immediate surroundings. He created works in a variety of media, from graphite drawings to wall frescoes, all of which exhibit a deeply modernist yet highly individualistic and contextually specific sensibility towards form, color, and composition.